We Understand the Value of Strong Collaborations

Poxel has built a solid foundation in the field of metabolic diseases, both validated through significant collaborations with strong partners in the industry and academia. Poxel is devoted to maximizing the therapeutic commercial potential of our pipeline. By combining our strong internal clinical development expertise in metabolic diseases with external partners, we can create powerful synergies and advance our goal to ultimately provide better treatment options for patients.

Our Industry Collaborators

  • Sumitomo Dainippon Pharma
  • Roivant Sciences
  • Enyo Pharma
  • Merck
  • DeuteRx LLC

We have a strategic development and commercialization agreement with Sumitomo Dainippon Pharma for the development and commercialization of Imeglimin in Japan, China and 11 other Asian countries. For Japan, we are jointly conducting the Phase 3 TIMES program for the treatment of type 2 diabetes and Sumitomo Dainippon Pharma will commercialize Imeglimin for this market. In China, South Korea, Taiwan and nine other Southeast Asian countries including Indonesia, Vietnam, Thailand, Malaysia, the Philippines, Singapore, Myanmar, Cambodia, and Laos, Sumitomo Dainippon Pharma will be solely responsible for the development and commercialization of Imeglimin.

We have a strategic development and license agreement with Roivant Sciences for Imeglimin in the U.S., Europe, and other countries worldwide that are not covered under the Sumitomo Dainippon Pharma agreement.

We have a licensing agreement with Enyo Pharma for our FXR (farnesoid X receptor) agonist. Enyo has completed a Phase 1 study and is currently conducting Phase 2 trials in Hepatitis B and NASH.

Through an agreement with DeuteRx LLC, we have acquired exclusive worldwide rights to a novel clinical stage drug candidate for NASH and a portfolio of additional deuterated drug candidates for metabolic, specialty and rare diseases. The lead candidate, PXL065 (DRX-065) is currently in Phase 1 studies and will be developed for the treatment of NASH.  

Our Academic Collaborators

  • CarMeN Laboratoire de recherche Cardiovasculaire, Métabolisme, Diabétologie et Nutrition, Université Lyon UMR INSERM 1060, France
  • INSA Lyon, Hospices Civils
  • Kobe University, Japan
  • Université de Grenoble U1042 & UMR_S 1055, France
  • Université de Rouen UMR INSERM 1096, France
  • Yale University, New Haven, CT, USA

We collaborate on an ongoing basis with academic leaders in metabolic disease, cardiovascular disease and mitochondrial dysfunction.

Interested in Collaborating with Us?

We'd love to hear from you and discuss partnership opportunities.

Contact Us