First drug approved in 2021

Poxel is developing a pipeline of several mid-to-late-stage drug candidates targeting the mitochondrial dysfunction. Imeglimin was approved as TWYMEEG® for type 2 diabetes in Japan in June 2021 and was launched in September 2021. Imeglimin has also successfully completed Phase 2 development in the U.S. and EU. PXL770 and PXL065 are in mid-stage development for NASH. We are also evaluating our AMPK activation and TZD platforms for other chronic and rare metabolic diseases with the objective to launch Phase 2a proof-of-concept studies in ALD mid-2022.

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Latest News

Poxel Announces Extended Cash Runway with Debt Restructuring Agreement and Equity-linked Financing Facility

Cash runway extended through at least February 2023 based upon debt restructuring agreement with IPF Partners (IPF) and equity-linked financing facility for up to EUR 6 million with Iris Capital Investment…

Read this Press Release: Poxel Announces Extended Cash Runway with Debt Restructuring Agreement and Equity-linked Financing Facility

Poxel Provides Corporate Update and Reports Cash and Revenue for the Second Quarter and First Half 2022

Cash runway extended through at least February 2023 based upon debt restructuring agreement with IPF Partners (IPF) and equity-linked financing facility with Iris Capital Investment (IRIS) As of June 30, 2022, cash…

Read this Press Release: Poxel Provides Corporate Update and Reports Cash and Revenue for the Second Quarter and First Half 2022

Poxel Announces the Publication of Two Preclinical Articles on X-Linked Adrenoleukodystrophy for PXL065 and PXL770

LYON, France--(BUSINESS WIRE)-- POXEL SA (Euronext: POXEL - FR0012432516), a clinical stage biopharmaceutical company developing innovative treatments for chronic serious diseases with metabolic pathophysiology,…

Read this Press Release: Poxel Announces the Publication of Two Preclinical Articles on X-Linked Adrenoleukodystrophy for PXL065 and PXL770
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Innovative Pipeline of First-In-Class Products

Our candidates are based on disease-modifying mechanisms of action that offer the potential for safer and more effective therapies for NASH and rare metabolic diseases.

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Innovative Pipeline of First-In-Class Products

Targeting Mitochondrial Dysfunction

Imeglimin was approved as TWYMEEG® for type 2 diabetes in Japan in June 2021 and will be marketed by our strategic partner, Sumitomo Dainippon Pharma, in 2021. Imeglimin has successfully completed Phase 2 development in the U.S. and EU. PXL770 and PXL065 are in mid-stage development for NASH. We are also evaluating our AMPK activation and TZD platforms for other chronic and rare metabolic diseases.

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Targeting Mitochondrial Dysfunction

Backed by Strong Leadership

Our highly-experienced clinical and regulatory teams possess the know-how and experience to successfully develop products within our pipeline.

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Backed by Strong Leadership